Friction coefficient is an important parameter in sheet metal forming especially in hot forming. Friction condition not only influences material flow but also affects the thermal conductivity between blank and tools. In this study, varied friction coefficient is introduced to the hot forming simulation of B-pillar made of ultra high strength steel sheet 22MnB5. Three curves of friction coefficient vs. temperature are investigated. All of the heat transferred by conductivity, radiation and convection are considered in the simulation. And the temperature-dependent material and process parameters are supplied. It is demonstrated that the coupling effect among the strength and hardness of the metals, the properties of the oxide film covering blank surface and viscosity of the lubrication oil leads to the fact that the friction coefficient changes with temperature instead of constant during hot forming. The friction coefficient curve characterized by increasing first then decreasing gives the best simulation results and then is followed by the one which is characterized by decreasing first then increasing. The constant friction coefficient is the last.