The advantages of CO2 Heat Pump water heater include: CO2 is one of natural refrigerants and does not affect the global environment as many other HFCs refrigerants; CO2 heat pump water heater can produce hot water up to 90 ,which is higher than HFCs heat pump water heater(about 55 ).So the application of CO2 Heat Pump water heater is potential. But the Working pressure of CO2 Heat Pump Water Heater is about 9~12Mpa and is 3-5times of HFCs heat pump water heater’. Gas cooler is one of important part for CO2 heat pump water heater, and it must meet the needs of not only pressurization but also heat transfer. So it is important to design gas cooler correctly. In the paper, one system of CO2 Trans-critical Cycle Heat Pump Water Heater is designed, and double-pipe gas cooler is designed The heat transfer characteristics of CO2 in gas cooler with water in double-pipe heat exchanger was experimentally investigated. Experimental results showed that the gas cooler can meet the need of trans-critical CO2 cycle heat pump water heater. All the work is valuable for the application of CO2 heat pump water heater.