Under the heavy traffic, the stress state of asphalt pavement structure has such a complex change that it is difficult for conventional pavement structural response calculation model to deal with. Therefore, "Pavement structure dynamic mechanical response model under complex stress condition" is established in this paper. Kinds of cases are calculated according to the characteristics of heavy vehicle. Then the FWD deflection test and dynamic strain test are carried out. Finally, the rationality of pavement structural response model calculation model is proved by comparing the test results with the theoretical model calculation results.