The first high-rise to be completed in Anhui Province in China adopts concrete-filled steel tubular frame- reinforced concrete tube composite structure, which can be classified as the out-of-codes hybrid structure. The structure analysis model is established through the use of the large-scale general finite element software ABAQUS. The dynamic plastoelastic analytical method based on explicit integration which is not theoretically simplified is used to directly imitate the nonlinear reaction of the structure subject to the seismic force. The deformation, internal force and the damage of the structure are studied through the dynamic plastoelastic time-history analytical method subject to the 7-magnitude rarely met earthquake. The calculation result indicates that the maximum inter-layer displacement angle is 1/366 on the X direction and 1/279 on the Y direction, both of which are smaller than 1/100, thus they meet the standards; except for the local cracks, no obvious compression damage is found on the main bearing wall, no plastic strain is found on the internal steel skeleton of the shear wall and the steel reinforcement of the edge member, and the shear wall is of good earthquake resistance performance. Lastly based on the loading and damage conditions of the components, suggestions for the improved design are put forward.