As excavation and precipitation involved in the foundation works will cause subsidence of the building foundation surrounding, grouting uplift technology is widely used to control settlement. In this paper, relied on rectification of one building, a three-dimensional finite difference model of grouting-soil-building interaction is established. Based on the method of imposed volumetric strain, the uplift process of grouting is simulated by expanding cell volume applied radial velocity to the grid nodes on the spherical slurry bubble. The variation regularity of surface deformation uplift, upper building deformation and internal forces on various stages of strata grouting are discussed and analyzed, and compared with the data on-site monitoring. The results show that the measured values and calculated values are in a good agreement. The method of applying the node speed to simulate non-uniform spherical expansion of multiple slurry bubble may predict the grouting uplifting preferably and provide a reference for design of grouting uplift and building rectification in the future.