The study on the rehabilitation of RC members with stainless steel wire mesh and polymer mortar indicates that debonding failure of reinforced layer is one of the main failure models. The key of the successful rehabilitation is that how to ensure the bond performance between reinforced layer and concrete. The experimental studies on the debonding failure between reinforced layer and concrete are carried out, and the influencing factors and characteristics of the debonding failure are analyzed, and the bond-slip curves are tested. At the same time, the program, ANSYS, is used to found the finite element models to simulate the experimental studies. The results show that there is an effective length of reinforced layer, which is extremely remarkable to the bond strength, and the main factors include curing age, interface roughness, concrete and polymer mortar strength. Based on experimental test and numerical simulation, the debonding strength formulas and bond-slip relationship of reinforced layer are presented, which can used to analyze some structures.