Crack control design of reinforced concrete structure focuses on the cracks caused by temperature and shrinkage stress, which is traditionally controlled through “resistance” or “relieving”. Related standard of China adopts easier way of expansion joint to relieve temperature and shrinkage stress. This method, however, is difficult to apply to modern super large buildings. Principle of “resistance in conjunction with relieving” was adopted in the design of Yongjin Plaza in Zhejiang province. No running through expansion joint was made in 136m×124m cast-in-situ multi-story concrete frame, instead, expansion joint is adopted in partial roof and floor. Steel bar quantity in coumns and beams was determined by factors of both load and temperature. Later-poured-zone, low expansion concrete, limited cement ratio and good curing measure were adopted to control cracks successfully.