In spring, autumn and winter, centralized air conditioning system frequently produces excessive cooling, if we use both air-energy saving system and water-energy saving system for directly cooling, replacing the chiller cooling, we can achieve the objective of energy saving. This paper introduces the air and water-energy saving system operation strategies to determine the operation control methods of different seasons. Through case analysis, it shows that this design is feasible. The system is stable and easy to control and management. It has obvious effect of energy-saving. If the air-energy saving system and water-energy saving system mode is adopted, the add-on investment of equipment can be recovered within one year, with a better economic benefits.