Paper Title:
EDC-Crosslinked Electrospun Silk-Fibroin Fiber Mats
  Abstract

Electrospun Silk-Fibroin (SF) mats were fabricated by electrospinning with regenerated Bombyx mori silk-fibroin/formic acid solutions. After spinning, the water soluble and mechanical properties of pure fibroin nanofibers were poor. So electrospun SF mats were crosslinked with N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride (EDC), a low cell cytotoxicity crosslinking agent, and N-hydroxysuccinimide (NHS), which can increase the reaction rate. The scanning electron microscope images indicated that the diameter of fibers increased with crosslinking reaction. When EDC/NHS reached to 7.5wt.%, the diameter of fibers achieved the maximum. The mechanical test showed that tensile strength enhanced after crosslinking with EDC/ NHS. While EDC/NHS reached to 7.5wt %, the rupture strength reached to (38.31±5.30) Mpa, and the breaking elongation ratio reached to (182.00±31.27) %. FTIR results showed the the proportion of β-sheet increased while random coil and α-helix decreased after treatment.

  Info
Periodical
Advanced Materials Research (Volumes 175-176)
Main Theme
Edited by
Lun Bai and Guo-Qiang Chen
Pages
170-175
DOI
10.4028/www.scientific.net/AMR.175-176.170
Citation
R. Liu, F. Zhang, B. Q. Zuo, H. X. Zhang, "EDC-Crosslinked Electrospun Silk-Fibroin Fiber Mats", Advanced Materials Research, Vols. 175-176, pp. 170-175, 2011
Online since
January 2011
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Guan Xian Dou, Xiao Hong Qin
Abstract:In electrospinning, non-woven fabrics are commonly used as substrates to receive polymer nanofibers. Nanofiber mats formed in this process...
247
Authors: Yun Hui Xu, Zhao Fang Du
Abstract:In order to develop cotton fabric underwear with the health care function, the cotton fiber was modified with the collagen (CMCF) using...
1415
Authors: Xiao Gang Liu, Li Wang, Chen Yu Fan, Shi Zhong Li
Abstract:Compositing with starch is an effective way to lower the cost of the poly (lactic acid)(PLA)-based biodegradable materials, while the...
207
Authors: Hang Bo Yue, Ying De Cui, Guo Qiang Yin, Zhen Yu Jia, Lie Wen Liao
Environmental Friendly Materials
Abstract:A novel class of environmentally friendly protein-based bioplastics—cottonseed protein plastic sheets (CP-sheets)—were prepared by...
1518
Authors: Shu Hua Wang, Jin Ming Dai, Hu Sheng Jia, Bing She Xu
Chapter 1: Textile Materials
Abstract:Cellulose fibers were chemically modified on surface by acrylamide polymerization and glutaraldehyde crosslinking. The chemical and...
43