Paper Title:
Characterization of Angiogenesis during Skin Wound Repair by Porous Silk Fibroin Film
  Abstract

Based on our experimental data of neovascularization of porous silk fibroin films (PSFF),in this study we characterized the formation of new blood vessel system at different periods. Firstly, we regarded a wound as two sections, namely, an interface layer and a material layer. Angiogenesis of the interface layer underwent three periods that were rehabilitation period of primary vascular plexus (postoperative 1st day-3rd day), rapid growth period (postoperative 3rd day - 7th day) and remodeling period (after the 7th day). In addition, angiogenesis of the material layer underwent initiation period (postoperative 5th day - 7th day), rapid growth period (postoperative 7th day - 13th day) and remodeling period (after the 13th day). According to the analysis results for angiogenesis, we realized that the efficacy of PSFF on repairing wound was reflected in coordination between infiltration of cells in the pores and angiogenesis, and in timeliness of the newly formed blood vessels’ extention from the interface layer to the material layer.

  Info
Periodical
Advanced Materials Research (Volumes 175-176)
Main Theme
Edited by
Lun Bai and Guo-Qiang Chen
Pages
181-185
DOI
10.4028/www.scientific.net/AMR.175-176.181
Citation
K. H. Zhan, L. Bai, G. P. Guan, H. Q. Dai, "Characterization of Angiogenesis during Skin Wound Repair by Porous Silk Fibroin Film", Advanced Materials Research, Vols. 175-176, pp. 181-185, 2011
Online since
January 2011
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Lun Bai, Jian Mei Xu, Qi Long Sun, Chuan Xia Di, Zheng Yu Wu
Abstract:In order to obtain porous silk fibroin films that suit all kinds of different tissue and organs, to design the configuration of the porous...
229
Authors: Guo Ping Guan, Lun Bai, Bao Qi Zuo, Ming Zhong Li, Zi Lin Sun, Zheng Yu Wu
Abstract:Neovascularization in biomaterials plays a key role in wound healing. In this paper, porous silk fibroin films (PSFFs) whose structure was...
1113
Authors: Kui Hua Zhan, Lun Bai, Hong Qin Dai
Abstract:We divide a solid tumor in vascular phase into a vascular layer, an oxygen-diffusion layer, an oxygen-resistant layer and a necrotic layer...
736
Authors: Zi Ling Sun, Lun Bai
Abstract:Porous Silk Fibroin Films(PSFFs) as dermis implant were used widely in biomaterials. To investigate angiogenesis in rat at different time...
1382
Authors: Kui Hua Zhan, Liang Xie, Xin Hong Wang, Bao Qi Zuo, Lun Bai
Chapter 2: Textile and Silk Materials Science, Properties
Abstract:Objective: To explore the effects of the biodegradability of biomaterial scaffolds on skin tissue regeneration and its neovascularization by...
79