Under the background of modern industrialization, the traditional process bursts out new vitality with unique hand-painted art taste and traditional culture connotation. On the basis of absorbing the essence of traditional handicrafts, in this paper the traditional silk hand-painted fabrics is focused. Its artistic character, fashion and practicability are discussed respectively. The second design methods based on modern science and art concept retain the original aesthetic characteristic, and furthermore do innovation in process, pattern and fabric design. The research results would be helpful to practical production design and satisfy the relative market.