With the assistance of anion surfactant sodium dodecyl sulphonate (SDS), spindle-shaped nanostructured lithium iron phosphate (S-LFP) was synthesized in glycol-water media via a novel refluxing method under N2 atmosphere. FeSO4, (NH4)2HPO4 and LiOH were used as Fe, P and Li sources, respectively. The crystal phases were analyzed by X-ray diffraction (XRD). The morphology and spindle-shaped nanostructure were observed by field emission scanning electron microscopy (FE-SEM). The results showed that the purity of the product was greatly influenced by the volume ratio of glycol to water. With the increase of the ratio, the crystal phases tended to pure LFP. On the other hand, with the increase of SDS amount, the particles tended to uniform and spindle-shaped morphology.