Paper Title:
Prediction of Antigenic Epitopes for Coat Protein of Potato virus Y
  Abstract

Potato virus Y (PVY) is one of the most important viruses that infect Solanaceous crops. In the study, the antigenic epitopes were predicted using computer-assisted analysis, and many potential regions of antigenic epitopes were located. Many properties of coat protein, such as the antigenic index, α-helix, β-sheet, β-turn, coil structure, hydrophilicity, surface probability, and flexibility, were analyzed with several algorithms in some softwares. Based on the rules for location the antigenic epitopes in the regions including β-turns and coil structures with the high hydrophilicity and surface probability, the predicted epitopes were located in the region of amino acid position 8-22, 24-38, 45-55, 240-255, respectively. It is helpful to prepare the antiserum of PVY based on the prediction result of antigenic epitope.

  Info
Periodical
Advanced Materials Research (Volumes 183-185)
Chapter
Environmental Biotechnology
Edited by
Yanguo Shi and Jinlong Zuo
Pages
1204-1208
DOI
10.4028/www.scientific.net/AMR.183-185.1204
Citation
S. H. Guo, C. L. Wang, H. Y. Yang, N. N. Zhang, X. Zhuang, D. Z. Cui, "Prediction of Antigenic Epitopes for Coat Protein of Potato virus Y", Advanced Materials Research, Vols. 183-185, pp. 1204-1208, 2011
Online since
January 2011
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Price
$32.00
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