Paper Title:
Preliminary Study on Extracting Technique and Biological Activity of Fucoidin in Undaria pinnatifida
  Abstract

To investigate extracting technique and potential biological activity of fucoidin in Undaria pinnatifid, a kind of marine organisms. Factors such as solid-liquid ratio (times), time of extraction (min) and temperature of extraction (°C) were chosen to be investigated to examine the best extracting technique. 50 mice were randomed to negative comparison group, positive comparison group and experiment groups. Mice were inoculated tumor stock S180. The negative comparison group were administrated with physiological saline, positive comparison group administrated with astragalus polyose(50mg/(kg•d)), and experiment groups administrated with fucoidin(100mg/(kg•d), 50mg/(kg•d), 25mg/(kg•d)). The tumors were peeled and weighted after 7 days. The best extracting condition is definite to be 100 °C, 60 times of water and 7h. The content of fucoidin in Undaria pinnatifida is 55.4% after preliminary purification. The tumor inhibition rate of experiment groups are 56.19%, 65.71% and 30.48%. The results of investigation on orthogonal experiments are reliable. And fucoidin in Undaria pinnatifida has certain antitumor effect.

  Info
Periodical
Advanced Materials Research (Volumes 183-185)
Chapter
Environmental Biotechnology
Edited by
Yanguo Shi and Jinlong Zuo
Pages
887-890
DOI
10.4028/www.scientific.net/AMR.183-185.887
Citation
Y. B. Ji, B. Yang, "Preliminary Study on Extracting Technique and Biological Activity of Fucoidin in Undaria pinnatifida", Advanced Materials Research, Vols. 183-185, pp. 887-890, 2011
Online since
January 2011
Authors
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Hong Yu Qi, Xiao Guang Yang, Rui Li, Hong Liang Wei
Abstract:Thermal barrier coatings (TBCs) have received increased attention for advanced gas turbine engine application. The oxidation damage plays an...
595
Authors: Jian Feng Di, Jun Yun Tang
Abstract:The relationships between the PANI content and the surface resistance of PANI composited conductive fabric were established by the design of...
844
Authors: Sheng Hua Lv, Rui Jun Gao, Di Li
Chapter 2: Applied Chemical Engineering
Abstract:A new polycarboxylate superplasticizer (NPC) was synthesized by radical copolymerization of maleic anhydride (MAH), sodium methylacryl...
606
Authors: Xian Yin Ping, Hui Sheng Zhuang
Chapter 5: Environmental Analysis and Monitoring
Abstract:The solid-phase microextraction (SPME) technique with on-fiber derivatization coupled to gas chromatography–mass spectrometry was evaluated...
1496
Authors: Xiao Fei Zhu, Tian Yi Li, Hou Zhuang Shan, Ling Niu, Lei Liu
Chapter 3: Metal Alloys and Steel
Abstract:The use of a silane coupling agent (3-aminopropyltriethoxysilane) to improve the anticorrosive property of low carbon steel was assessed by...
136