Paper Title:
Study on Reversibility of Genetic Toxicity of TDI in Mice
  Abstract

Study on whether genetic toxicity of toluene diisocyanate (TDI) is reversible. This paper detected Chromosomal aberrations and content of RNA & DNA. Chromosome aberration rate and the RNA/DNA ratio of TDI 1/4LC50 and 1/2 LC50 dosing exposure group were higher than negative control group significantly (P<0.01). There was no significant difference between 1/4LC50 and 1/2LC50 (P>0.05).The results showed that the damage of TDI on chromosomes and DNA was repairable, but can not be repaired completely.

  Info
Periodical
Advanced Materials Research (Volumes 183-185)
Chapter
Environmental Biotechnology
Edited by
Yanguo Shi and Jinlong Zuo
Pages
905-909
DOI
10.4028/www.scientific.net/AMR.183-185.905
Citation
M. Yu, Y. B. Ji, "Study on Reversibility of Genetic Toxicity of TDI in Mice", Advanced Materials Research, Vols. 183-185, pp. 905-909, 2011
Online since
January 2011
Authors
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: T. Ivanova, I. Smirnova, T. Kondrashova, Yeon Sook Yun, Jie Young Song, Young Soo Han
Abstract:Spontaneous levels of the chromosome aberrations in the peripheral lymphocytes of 173 women were analyzed in the course of a medical...
680
Authors: Qu Min
Environmental Biotechnology
Abstract:Giemsa C-banding patterns and karyotype of chromosomes were analyzed in the root-tip cells of diploid Thinopyron elongatum. A modified seed...
877
Authors: Chang Hong Guo, Wen Yue Su, Wen Wen Cong, Lei Wu, Dan Wang
Chapter 1: Environmental Chemistry and Biology
Abstract:When the gametocidal chromosome 3C from Aegilops triuncialis was introduced into common wheat, it was preferentially transmitted and it had...
228
Authors: Chang Hong Guo, Lei Yang, Chun Ying Liu
Chapter 1: Environmental Chemistry and Biology
Abstract:Thinopyrum elongatum, a wild relative of wheat, can be used as an excellent source of disease and abiotic stresses resistance and carries...
236
Authors: Jian Liu, Yang Yang, Fen Ju Liu, Qing Fang Liu
Chapter 5: Bio- and Medical Engineering
Abstract:To evaluate the teratogenicity of the dental implant and provide a basis for safe applications of medical products. Chromosome aberration...
420