Paper Title:
Taurine Induces the Apoptosis in Pulmonary Artery Smooth Muscle Cell
  Abstract

As an endogenous anti-damage material in organism, Taurine (Tau) stems from food and almost resides in all animals’ cells by means of liberation,which could be found in diverse biological actions, including protection against ischemia-reperfusion injury, modulation of intracellular calcium concentration, and antioxidant, and blood pressure-lowering effects[1]. It also has an effect that inducing apoptosis in certain kinds of cells. Our results showed that Tau can degrade cell viability, mitochondrial potentials, and the expression of Procasepase-9 in PASMCs. In conclusion, Tau induces apoptosis in PASMCs through mitochondrial-dependent pathway.

  Info
Periodical
Advanced Materials Research (Volumes 183-185)
Chapter
Environmental Biotechnology
Edited by
Yanguo Shi and Jinlong Zuo
Pages
937-941
DOI
10.4028/www.scientific.net/AMR.183-185.937
Citation
X. D. Zhang, J. J. Sheng, F. H. Zhao, D. L. Zhu, "Taurine Induces the Apoptosis in Pulmonary Artery Smooth Muscle Cell", Advanced Materials Research, Vols. 183-185, pp. 937-941, 2011
Online since
January 2011
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Price
$32.00
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