The new method is put forward for machining bigger holes of carbon fiber reinforced plastics (CFRP) in the face of the existent problems. The core drill is applied to machine CFRP from two end-faces according to regular order. The thrust is less than felted intensity between adjacent layers of CFRP in their whole process. Through special experiment, the method is not only economical but also convenient. The finishing workpieces have not defects such as burrs, avulsion and delamination. In addition, its precision and efficiency are very satisfactory to manufacturer.