The target of this paper is to design a high speed drilling machine suitable for printed circuit board with micro-hole of 0.1 mm diameter, which has drilling force measuring function and rapid change spindle function. Therefore, in this paper, the main principles of module partition for drilling machine were analyzed. Module partition was conducted for high speed drilling machine of Printed Circuit Board (PCB), as well as using modular components combine PCB high speed drilling machine. Then, performance testing and simulation of dynamic modeling were carried out on the modular PCB high speed drilling machine. The results show that the modular PCB high speed drilling machine has good performance, enough stiffness, better stability and meeting the design requirements. The modular partition laid the foundation for further study on the module creation and reconfiguration of PCB drilling machine.