The aim of this research is to design and fabricate the machine for production of bio-oil from agricultural residues in northeast of Thailand. Experiment: to produce the bio-oil from corn-stalk, husk and sawdust with 200 g/hr of capacity, 500°C of reactor temperature, -10°C of condensing unit temperature and testing of the mechanics and chemical property. The results showed that the yield of bio-oil from corn-stalk husk and sawdust are 17.40 18.40 and 22.40, respectively. According to the physical characterisation of the products, it was found that the bio-oil produced in this work showed similar properties to the bio-oil from commercial production. The results found in this research are useful for the development of a larger-scale bio-oil production unit, which is an on-going project at the Faculty of Engineering, Maha Sarakham University.