Corrosion behaviors of X80 pipeline steel were investigated in different simulated alkaline soil solution using electrochemical test, EDS coupled to SEM and weight loss method. The results showed uniform corrosion was happened on X80 steel in Shanshan and Hami simulated solution, and local corrosion was the main failure mode for X80 steel in Yumen simulated solution. The ranking of corrosion rate of X80 steel from the biggest in simulated solution was Hami, Shanshan and Yumen. With the increasing of immersion time, a dense Ca2+ deposited layer was formed on the surface of X80 steel, which could inhibiting the Cl- effects on the corrosion of X80 steel in Shanshan and Hami solution. The SO42- competition absorbed effect could provide certain corrosion protection for X80 steel in Yumen solution at the early corrosion stage.