When applied in E-Business, the technology of Web Services based on SOAP protocol can promote integration of E-commerce and distributed application. But it has some potential problems of security. Through research of technology correlated SOAP, combined with E-business safety analysis, the paper designs a kind of secure E-Business application model based on SOAP protocol. It includes SOAP secure disposal and access controller, and is realized by J2EE. The model makes the SOAP messages transmit safely and solves the secure problems of E-Business. It has great significance for popularization and application of E-commerce.