The stress corrosion cracking (SCC) susceptibility of X80 pipeline steel, which was used in the Second West-East Gas Pipeline, was investigated in simulated soil solution of Xinzhou in Hubei province of China. The SCC susceptibility was studied using the slow strain rate tensile (SSRT) tests in which different potentials were applied. The fracture surfaces were observed using SEM. X80 steel was susceptible to SCC in simulated solution. The SCC was not serious with the anodic potentials applied. The fracture mechanism was anodic dissolution. But the SCC was affected obviously with different cathodic potentials because of the different influence of the hydrogen.