With the aircraft structure design criterion from traditional static strength design to damage tolerance design and with the independent research and development of new-type civil turbofan regional aircraft and the implement of the plan to develop the country's own large passenger jets in China, it is essential to do some researches on casting TC4 alloys for the lack of the data of fatigue properties. The detail fatigue rating cut-off (DFRcutoff) values of casting TC4 alloys are measured and calculated by double dots method, the thresholds in fatigue crack propagation and the fatigue crack growth rates at different stress ratios are studied and the fatigue fracture at different stress ratios are observed by scanning electron microscopy. The results show that DFRcutoff value by double-dot method is 375.83 Mpa. The thresholds of fatigue crack propagation decrease with the increase of the stress ratio, whereas the fatigue crack growth rates increase with the increment of the stress ratio and the relationship curves between fatigue crack propagation rates and the stress intensity factor range have been obtained. Moreover, SEM observations indicate that the fatigue trips become wide with the increasing of the stress ratio.