A few experiments are conducted to investigate the effects of different solidification process on the physical hardness and compressive strength of the home-made bone cement. 24 bone cement samples under different mixing conditions are prepared. The compressive strength, hardness and phase composition of bone cement samples are measured with electronic universal machine, Shore hardness tester and X-ray diffraction(XRD) respectively. The results show that the maximum compressive strength of 24 samples is 96.27MPa, and obviously superior to that of the clinical application of bone cement. The hardness of bone cement of group C( powder 20g and fluid 10ml, 80.43HD) and group D(powder 20g and fluid 12ml, 86.60HD) is higher than 80HD which is the clinical requirement.It is found by X-ray diffraction that the higher crystallinity could produce finer grain, which results in higher compressive strength and hardness with better ductility and toughness. Giving consideration to compressive strength and physical hardness and crystallinity of D3(20g:12ml, with stirring speed as 30 times/min and stirring time as 90 seconds), the solidification condition is best.