It is well-known that in modern through arch bridges the suspenders are important components since they connect the bridge deck and the arch ribs. When the suspender break happens, the other components of the through arch bridge will be impacted successively. Sometimes, the collapse of bridge deck may be induced by the possible suspender break. In this paper, the impact effect on the remaining components of the through arch bridge due to the suspender break is studied and obtained by appropriate simulation and time-history analysis using the comprehensive commercial software ANSYS, which is based on a real through arch bridge. The study in this paper will be helpful to carry out the reasonable design of the through arch bridge.