To analyze the relationship of brake performances and its influence factors, a kind of tire drum test-bed was designed. The gradation principle of flywheels was proposed based on the double multiplication method and an inertial system with eight steps of flywheels was put forward. The inertia-mass of tire load ranging 400 from 5000 kilograms was divided into 256 levels with the accuracy of ±10 kilograms. The dynamics simulation model was built using SOLIDWORKS and ADAMS. The program of acceleration and brake testing were schemed. The feasibility and accuracy of design methodology of test-bed inertial system were verified by the comparison analysis of simulation and road test. The accurate matching between the moment of inertia of test-bed inertial system and tire load was realized.