Gyöngyösoroszi is an abandoned lead-zinc sulphide ore mining area in Hungary. The diffuse pollution sources of mining origin identified in the area and the residual pollution after removal of the point sources will be subjected to combined chemical- and phytostabilisation. To select the best chemical stabiliser laboratory scale experiments were performed in microcosms. The following chemical additives were tested in various concentrations: three different fly ashes, lignite, alginite, hydrated lime, raw phosphate, iron hydroxide wastes from drinking-water treatment, red mud and the mixture of selected ones. The stabilisation of toxic metals in the soil was monitored by an integrated methodology, which combined physico-chemical analysis with toxicity testing. Based on the chemical analytical and the bacterial and plant toxicity test results, one of the tested fly ash types was the most effective: the mobile Cd and Zn concentration decreased by 50–99% in the fly ash treated contaminated soil, the bacterial and plant toxicity decreased by 30-70%, and the bioaccumulated metal amount by 70%. The combination of lignite, alginite, lime and phosphate was also efficient.