Compared with hydraulic press, pneumatic press has many prominent advantages such as low energy consumption, no pollution to environment, fast speed and high efficiency etc. However, its critical disadvantage is that its pressure is much slower than that of the hydraulic system, which results in lower output force. An innovative pneumatic press driven by a new composite pneumatic-mechanical transmission mechanism is presented in this paper. With the aid of the force amplifier of two-step serial toggle-lever, the output force of the piston is amplified twice and the amplification factor can up to 20. Besides, two innovation design plans were discussed, namely, the single-cylinder-single-piston press and the single-cylinder-double-piston press. Moreover, the single-cylinder-double-piston press is remarkable in harmonious symmetry and technical performances.