The offshore region of Haizhou Bay is characterized by intense anthropogenic activities. And the study on comparative analysis of water quality status in this offshore region has attracted more and more attention of the researchers and decision-makers. In this paper, comparative analysis on water quality status of different samples in Haizhou Bay during May 10-21, 2007 was studied by principal component analysis method (PCAM). The water quality status in Haizhou Bay was compared and analyzed by using 13 samples, with DO, SS, Active Phosphate and Petroleum impact factors. Based on the PCAM analysis procedures, the comparative analysis results of water quality state in Haizhou Bay show that the spatial order from good to bad is determined as follows: JS03> JS01> JS04> JS07> JS02> JS09> JS05> JS06> JS13> JS10> JS12> JS08> JS11.