As e-commerce is widely used in modern enterprises, it’s necessary for enterprises to innovate their financial management modes so that corporate financial management could adapt to the requirements of the development of informationization. This research firstly studies the background in which Informationization of financial management based on E-commerce has developed and the connotation of the concept. Then, it analyzes the basic features of financial management in the e-commerce environment and points out the major deficiencies of traditional financial management. Finally, it makes suggestions on how to build an informationization system for financial management based on e-commerce. It is hoped that these analyses and suggestions would be helpful in working out a new mode of corporate financial management.