The sol-gel method was made use of to prepare TiO2 thin films and Ni2+ doped TiO2 thin films. The static contact angle measurement was employed to estimate the wettability of prepared films, and the crystalline phase and surface morphology were characterized by XRD and AFM, respectively. The film’s photo-catalytic property was tested according to degradation of methyl orange solution. The results indicate that 1.0% molar ratio of Ni2+ and TiO2 makes hydrophilicity and photo-induced hydrophilicity of the doped thin film increasing, however, at the same time its photo-catalytic property decreases slightly. It is suggested that the mechanism of photo-induced hydrophilicity of TiO2 thin film is different from the one of photo-catalytic oxidation decomposition property.