Recently guidance system is becoming more popular, as more people realize its benefits. There have been many developments on campus guidance system (CGS) in personal digital assistant (PDA) and smart phone. The building and promotion of the energy efficient location determination method is an important part of CGS. The cellular-based location determination using RSS from cellular network is more immediately, power-effective, and easy to deploy and maintain than traditional methods. In this paper, we design the CGS which provides the fingerprint position algorithm (FPA) using RSS from cellular networks and location-based service (LBS) for user reference. In experiments, we compare the estimated positioning information with the real information from global position system (GPS) receiver. The results show that the error of location estimation using FPA is about 9.92 meters. This approach is feasible to be applied to CGS.