The interface properties of carbon fiber(CF) within the composite material has a great effect to its functional characteristics. The work is focused on the research of CF electro-mechanical response after its surface modification using acetone and nitric acid oxidation. With characterization by XPS and SEM, there exist the various changes on the CF surface not only the chemical elements or chemical groups. With changing CF’s resistance under uniaxial tension, the CF has differerent electro-mechanical response to loading force. Through statistical analysis, the research shows the sensibility of CF to the electro-mechanical effect can be improved by the surface modification with acetone process or nitric acid oxidization.