With the detonation of information, the requirement of real-time data collection has been paid increased attention. It is more difficult that a real-time information system in practical application not only considering its convenience of maintenance, credibility of performance and flexibility of configuration, but reducing its developing cost as well. Therefore, to borrow the idea from the layered design for software system, a virtual layered concept was presented in this paper. And also a virtual layered design scheme for real-time information system based on the concepts of virtual layer and layered design was built to provide a flexible configuration method for development of series systems in different applications. The practices show that this scheme has strong flexibility, good efficiency and integrated optimization.