The change of surface of Cd0.9Zn0.1Te crystal morphology after irradiation by pulsed Nd:YAG laser has been studied. Thermogradient effect (TGE) has the main role in the interaction process of laser radiation with semiconductors. A change of the irradiated surface relief has been observed by atom force microscope. Self-organizing nano-cones are observed on the irradiated surface of Cd0.9Zn0.1Te crystal at intensity of the laser in the range of 4.0 – 12.0 MW/cm2. A graded band gap structure with optical window was formed at the top of nano-cones.