According to the practical situation (loaded by the second time), nine pieces of prestressed concrete hollow slabs which had been reinforced with CFRP were experimented on. And symmetric load was putted on the three-point of the hollow slabs. In this paper, the effects of different pasting methods and quantity of CFRP on mechanical performance and reinforcement effect of prestressed concrete hollow slabs which were damaged in varying degrees were studied. And the ultimate bearing capacity, failure mode, types of cracks and load-deformation curves of test specimen after being reinforced was analyzed systematically. After contrasting and analyzing the trial value of prestressed concrete hollow slabs, a simple, economic and reasonable reinforcing program was obtained.