PPS and PA6 were blended to improve the mechanical properties of the large diameter PPS monofilaments. The influence of the structure of the blends on the blending monofilaments, the comparative analysis with relevant polymer monofilaments and the acid and alkali resistance were studied in this article. The results demonstrated that: the mechanical properties of the PPS monofilaments were improved. The tensile strength and the collaboration strength of the monofilaments increased. The toughness of the PPS monofilaments increased. Simultaneously, the acid resistance and the alkali resistance of the PPS monofilaments were retained in the PPS/PA6 blending monofilaments.