In fixed-fluidized bed reactor, laboratory evaluation of different catalyst, raw materials and process parameters can be implemented, so it has wide applications in the refining process. In this study, we focused on small fixed-fluidized bed reactor, using Eulerian-Eulerian two-fluid model, simulated the gas-solid flow behavior in it. Gas residence time distribution was measured in order to characterize macro-mixing. At the same time, by changing the reactor structure and operating conditions, we studied their effects on gas-solid macro-mixing characterization. The results show that the effects of structural parameters are larger than operating conditions, and different parameters have different effects. Different parameters can be adjusted to change the gas-solid macro-mixing characterization in small fixed-fluidized bed reactor. Therefore, the small fixed-fluidized bed reactor can provide better results in more application areas.