Paper Title:
Core Cross-Linked Polyethylene Glycol Oleate Micelles as Novel Drug Carriers
  Abstract

Polyethylene Glycol Oleate was synthesized by esterification of polyethylene glycol and Oil acid using DMAP as a catalyst. The double bonds of the product in the core of micelles were cross-linked by the initiation of (NH4)2S2O8 during the micelles formed. Applications of the noncross-linked and cross-linked polyethylene glycol oleate in drug delivery were studied, which indicates that drug efficiency decreased after micelles were core cross-linked, but release rate of MTX from core cross-linked micelles seems slower than that from noncross-linked micelles.

  Info
Periodical
Advanced Materials Research (Volumes 236-238)
Edited by
Zhong Cao, Yinghe He, Lixian Sun and Xueqiang Cao
Pages
1770-1774
DOI
10.4028/www.scientific.net/AMR.236-238.1770
Citation
Y. L. Guo, B. Q. Wang, J. Zhao, Z. S. Cui, "Core Cross-Linked Polyethylene Glycol Oleate Micelles as Novel Drug Carriers", Advanced Materials Research, Vols. 236-238, pp. 1770-1774, 2011
Online since
May 2011
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Price
$32.00
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