Paper Title:
Synthesis and Characterization of Dual-Magnetic Thermosensitive Microspheres
  Abstract

Fe3O4 nanoparticles and poly(N-isopropylacrylamide-co-methacrylic acid) were combined to form dual-magnetic thermosensitive microspheres. The results of fourier-transform infrared (FTIR) spectroscopy, transmission electron microscope (TEM) and thermogravimetric analyzer (TGA) confirm that the microspheres are characterized with a magnetic Fe3O4 core, a poly(N-isopropylacrylamide-co-methacrylic acid) shell, and an average diameter of about 150-300nm. Spectra of wide angle X-ray diffraction (WAXD) indicate that the copolymer on the surface of Fe3O4 nanoparticles shows no influence on the inverse cubic spinel phase of Fe3O4. The lower critical solution temperature (LCST) of the thermosensitive copolymer-shell is about 39°Cas determined by a turbidimeter. Besides, the microspheres exhibit an obvious advantage using magnetic separation, and can be heated through an external alternating magnetic field to generate thermal effects, thus possess dual-magnetic responses (including magnetic delivery and magnetic-thermal effects). The synthesized microspheres with dual-magnetic and thermosensitive responses have potential applications in a magnetic drug-targeting delivery system for controlled drug release.

  Info
Periodical
Advanced Materials Research (Volumes 236-238)
Edited by
Zhong Cao, Yinghe He, Lixian Sun and Xueqiang Cao
Pages
1867-1872
DOI
10.4028/www.scientific.net/AMR.236-238.1867
Citation
L. F. Cai, Y. Q. Wen, Z. Y. Lin, "Synthesis and Characterization of Dual-Magnetic Thermosensitive Microspheres", Advanced Materials Research, Vols. 236-238, pp. 1867-1872, 2011
Online since
May 2011
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Dong Hoon Lee, Hye Suk Park, Dong Wan Seo, Whan Gi Kim
Abstract:Novel bisphenol-based wholly aromatic sulfonated poly(ether sulfone-ketone) copolymer and organic-inorganic composite membranes were...
97
Authors: Wu Lei, Xin Gen Xie, Feng Yun Wang, Ming Zhou Xia
Abstract:A novel conducting copolymer, was successfully achieved by electrochemical oxidation of the monomer mixtures of 3, 4-ethylenedioxythiophene...
1662
Authors: Hong Yan Tang, Long Chen
Abstract:A novel idea to prepare Polymethacrylimide (PMI) foam is presented in this paper, in which PMI foam was prepared by two steps, the butyl...
1309
Authors: Dong Xia Zhang, Wen Hui Hu, Fang Ping Wang, Lin Ke Xue, Xin Zhen Du
Abstract:An amphiphilic graft copolymer with poly(acrylamide-methacrylate) as a main chain and octylphenyl polyoxyethylene as side chains...
3337
Authors: Peng Qu, Chi Zhang, Hui Min Han, Jing Xu, Ye Zhou, Jing Wang
Chapter 2: Polymer Chemistry
Abstract:D-glucose was used to react with methyl methacrylate (MMA) (and methyl acrylate(MA) as comparison) to generate new biomass-based materials in...
311