The paper attempts to investigate the interaction between sandstones and some drilling fluids components, including inorganic salts and surfacant ZJBS, as well as the influence on ROP imposed by them. The mechanism of the experiment is initially achieved. The results show that Al3+ and ZJBS both can improve the ROP. The ROP will be enhanced by 33.7% when AlCl3 concentration is up to 0.01mol/L, and Al3+ enables zeta potential of the solution containing cuttings shifted from negative value to zero , and finally to positive value by means of analyzing zeta potential, which contributes to the significant improvement of ROP when zeta potential is greater than -10mV. Higher surface free energy created by the close-to-zero zeta potential is conducive to crushing rocks, which in turn increases the ROP and meanwhile reduces drilling costs. The ZJBS also can change the zeta potential of the cuttings and it has good compatiblity with sandstone. When its concentration is up to 0.01mol/L, the permeability rate of ZJBS is 15 times than that of distilled water. The ZJBS can effectively improve the efficiency of interaction between drilling fluids and this will be helpful to enhance the ROP.