For the arrangement of suspender and arch rib in the combination of beam and arch bridge, the finite element model is established according to the background of practical engineering. The influence of the variations of structure design parameters on structure characteristics of the static and dynamic is analyzed. The calculation results show that the different layout of suspender has small effect on the axial force variations of tie beam and arch rib, but has bigger influence on the bending moment of partial section. The structural transverse basic frequency augments with increase of arch rib leaning-angle, the vertical and twisting basic frequency is larger when the leaning suspender and netted suspender are used. The arrangement of suspender and arch rib should be optimized in the design of similar bridge.