As the deterioration of environment, the effect of acid rain on concrete structures is even more serious. The durability problems caused by acid rain are increasingly concerned by the worldwide. In this paper, the method to simulating acid rain solution in laboratory is proposed and the cyclic soaking-drying to accelerate the acid rain attack is introduced on the basis of the survey and analysis on the components of acid rain around China. Considering that the majority of concrete structures are actually under loads, the load devices for durability test are analyzed, and the devices suitable for the multi-factor durability tests are adopted. The above works will be helpful to carry out the neutralization tests and establish the predicting model of neutralization depth for fly ash concrete.