On the basis of summary and analysis of the characteristics of concrete hollow blocks and composite masonry walls, this paper puts forward the concept of composite masonry wall with condensed core columns. Regarding the distance between core columns (s=600mm and s=1200mm) as the main influencing factors, two composite masonry walls were designed and built to carry out the axial compression capacity experimental study. The results of the study show that the composite masonry wall with condensed core columns can greatly improve the ultimate axial compression capacity of the wall, delay the fracture process, and influence the failure modes. In the entire experiment, the deformation of concrete hollow blocks and core columns was basically the same, and can work in coordination. The stress mechanism of the composite masonry wall which had splitting fracture changed from the composite masonry wall to the (weak) frame structure, which finally formed column hinge and got destroyed. The experimental results of this paper can provide a new way for the application of concrete hollow blocks as main wall materials in the field of high-rise buildings. The establishment of axial compression capacity formula and the eccentric compression performance of the composite masonry wall with condensed core columns deserve further study.