To large span spatial structures, the displacements and internal forces caused by temperature loads and support settlements cannot be ignored. Beijing Jiangtai winter garden mainly consists of reticulated shell and glass curtain wall. The reticulated shell is composed of 9 spatial arches and other common frames, thus it can be seen as arch-reticulated shell hybrid structure. The two ends of the arches are supported at the top of steel columns and concrete walls separately. The glass curtain wall is fixed to vertical cables. This paper chose eight load cases including temperature loads and support settlements, and used ANSYS to analyze static responses of the structure under such load combinations. The comparative results showed that temperature loads had more effect on the structure’s load bearing capacity than support settlements. And the superiority of hybrid structures was fully embodied in the conclusions of this paper.