The seismic behavior of a single-story ten-bay confined masonry structure was investigated using substructure pseudo-dynamic tests. Only one bay of the prototype was regarded as the test model and the remainder was regarded as numerical model. The test results show that the test model withstood, with slight damage, strong earthquakes with peak ground acceleration of 1600 gal. It is found that prototypes of the tested type exhibited satisfactory seismic performance. Hence, the confinement can be reduced if the budget of the building is limited.