The curves of stress versus strain along spruce wood axial, radial and tangential directions are gained by static compression experiments. Moisture content and density of the spruce wood are 12.72% and 413 kg/m3 respectively. The results indicate that spruce compression process includes elastic, yield and compaction phases. Failure modes of spruce subjected to axial compression are fiber buckling and wrinkle. And failure modes under radial or tangential compression are wood fiber slippage and delamination. Axial compression yield strength is about nine times as that of radial and tangential compression. Radial and tangential compression yield strengths are almost equal. Energy absorption efficiency and ideality energy absorption efficiency of spruce along different loading directions are analyzed. And theory analytic solution to single wood cell buckling under axial compression is done. The obtained expression shows that the mean limit loading is relative to yield stress, cell structure dimension and wrinkle length for complete wrinkle cases.