Due to economical and serviceability reasons, local scour must be considered in the design of bridge piers. Although beds of natural rivers consist of nonuniform sediments, but most researches in this subject were carried out with uniform sediments. In nonuniform sediments case, the effect of sheltering of the finer particles by the coarser ones may alter the scour process. In this paper, the time-variation of local scour with nonuniform sediments around a cylinder pier is simulated using SSIIM software. This study shows that the SSIIM is capable of predicting the temporal evolution of local scour in bridge piers with nonuniform sediments.