Due to high maintenance and production costs of conventional asphalt pavements in recent years, substitution of concrete pavements has been taken into account. One important factor of such pavements is the long-term performance. The substitution of pozzolanic materials with existing cement in the mixture is a common choice to improve the durability factors and to increase the long term compressive strength. Owing to this change in cementitious materials, a general anticipation of the pozzolanic behavior to be observed is that the early age compressive strength gets decreased. On the other hand, this defect will be compensated in the long-term compressive strength. Furthermore, as conventional loads of road pavements are concerned, the tensile and flexural strengths have their own importance. Regarding these two factors, the related tests were also performed and the results were analyzed. The main purpose is to find the optimum material among these 2 types of pozzolanic supplements and its percentage of substitution with the preference of having the best average strength in both long and short term performances. Altogether, the natural pozzolan had better performance than limestone powder.