The aim of this study was to evaluate the influence of mix proportion parameters on anti-permeability of green high performance concrete (GHPC) and find out the main influencing factors. Applying grey relational analysis method, the relational grades between the influencing factors and diffusion coefficient of Cl- of GHPC were calculated. Besides, the sequence result of influencing degree of the factors to affect the anti-permeability was obtained. The result shows that the importance of the factors affecting anti-permeability of GHPC has following sequence: water-binder ratio> sand ratio > dosage of cement> dosage of water reducing admixture > dosage of mineral fillers > dosage of fly ash. In order to improve anti-permeability of GHPC, water-binder ratio and sand ratio must be controlled strictly.